Cholesterol drug shrinks plaque


Cholesterol drug shrinks plaque

NEW ORLEANS

For the first time, a new drug given along with a cholesterol-lowering statin medicine has proved able to shrink plaque that is clogging arteries, potentially giving a way to undo some of the damage of heart disease.

The difference was very small, but doctors hope it will grow with longer treatment, and any reversal or stabilization of disease would be a win for patients and a long-sought goal.

The drug, Amgen Inc.’s Repatha, also drove LDL, or bad cholesterol, down to levels rarely if ever seen in people before. Heart patients are told to aim for below 70, but some study participants got as low as 15.

5 students stabbed in boys’ locker room

OREM, UTAH

As a group of boys at a Utah high school changed Tuesday morning into gym clothes for physical education class, a straight-A student pulled out a knife in the locker room and stabbed five of his classmates, sending the injured running for their lives and covered in blood, police said.

The 16-year-old suspect with no record of disciplinary trouble also stabbed himself in the neck and was cornered by school workers until a police officer assigned to Mountain View High School got to the locker room and subdued him with a Taser shot.

The five victims are expected to survive, hospital officials said Tuesday afternoon. The two most seriously injured were in critical but stable condition, according to Utah Valley Hospital.

The suspect was treated and released after the attack.

Denver allows pot in bars, eateries

DENVER

Denver has approved a first-in-the-nation law allowing people to use marijuana at bars, restaurants and other public spaces such as art galleries or yoga studios.

The catch: Patrons could use pot as long as it isn’t smoked, and the locations would have to seek the approval of neighbors.

Denver voters approved Proposition 300 as eight other states legalized marijuana for medical or recreational purposes last week.

Russia announces operation in Syria

BEIRUT

Russian missiles pounded opposition targets in Syria on Tuesday, the start of a much-anticipated offensive, while activists reported the resumption of bombing in rebel-held neighborhoods of Aleppo for the first time in nearly a month, apparently by Syrian government warplanes.

The Russian blitz began hours after President Vladimir Putin and U.S. President-elect Donald Trump discussed Syria in a phone call and agreed on the need to combine efforts in the fight against what the Kremlin called their No. 1 enemy – “international terrorism and extremism.”

Russia said its offensive, using long-range missiles and its carrier-borne jets in combat for the first time on opposition areas in Syria, focused on rebel-held northern Idlib province and parts of the central province of Homs. The new offensive was a sharp snub to the Obama administration and its policy toward Syria, and augurs a major escalation in the coming days that would put tens of thousands of civilians in serious danger.

Clamoring for supplies

MOSUL, IRAQ

Explosions and gunfire rattled parts of eastern Mosul and Islamic State militants fired mortars from apartment windows Tuesday as Iraqi special forces waged fierce urban combat in the country’s second-largest city.

Hundreds of civilians filled the streets clamoring for food and cigarettes in recently retaken neighborhoods where supplies were running low. Some of the troops handed over their own rations.

Associated Press