Rebound effects after eliminating antiperspirants are surprising

Q. I work in cancer research. About 10 years ago, most of the women in my office decided to stop wearing antiperspirant because of the uncertainty of adverse health effects.

We all had amazingly similar experiences. Most of us immediately had an increase of smelly perspiration that tapered over a year. We used frequent underarm toweling and added baking-soda-based underarm powder for meetings. Fortunately, once we got past the rebound period, there were virtually no problems.

I suspect that antiperspirant rebound is like so many other problems caused by living in the age of chemistry: It fixes a short-term problem but causes a long-term one.

A. Your story surprised us. We’re familiar with rebound congestion after stopping nasal-spray decongestants, or rebound hyperacidity after discontinuing acid-suppressing drugs. We never imagined such an effect after eliminating antiperspirants.

We found that some researchers have studied this question. They discovered that antiperspirant use changes the balance of bacteria in armpits (PeerJ, Feb. 2, 2016). According to one scientist, antiperspirants encourage the growth of Actinobacteria that create unpleasant odors (Archives of Dermatological Research, October 2014). Stopping the antiperspirant does appear to promote bacterial growth. This might account for the rebound body odor you and your colleagues experienced.

Q. My wife died because of a medical error. A serious kidney problem led to a biopsy and a prescription for steroids.

While she was in the hospital, another doctor noticed a possible blood clot in her arm and started her on a regimen of blood thinners without telling us. As a result, her biopsy bled badly. Even though she was operated on to stop the leak, she deteriorated.

A hospital-acquired infection in her leg could not be healed. Her intestines became impacted, and 13 weeks later, she died. I do not understand why the second doctor did not notice that she’d had a biopsy, which would make an anticoagulant inappropriate.

A. We are so sorry to learn of this tragic outcome. Patients or their family members must always be informed of hospital treatments and double-check for possible mistakes. Our book “Top Screwups Doctors Make and How to Prevent Them” offers checklists to help people be extra-vigilant.

Q. I have sleep and prostate problems. I take one Advil PM each night, along with Crestor to control cholesterol and Unisom for insomnia. I am convinced that the Advil helps relax my prostate and limits me to one bathroom visit per night.

I can’t tolerate side effects from prescription drugs such as tamsulosin (Flomax) and finasteride (Proscar). Is Advil dangerous if taken regularly?

A. There is evidence to suggest that nighttime NSAID use may reduce trips to the bathroom (Urology, October 2008). Ibuprofen, the ingredient in Advil and Motrin, is an NSAID. The downside is that regular use of such drugs may affect kidney function or increase the risk of stomach irritation and ulcers, high blood pressure, heart attacks and strokes.

We worry about your double dose of diphenhydramine from Advil PM and Unisom. It can make people feel sluggish in the morning and may affect brain function.

2016 King Features Syndicate, Inc.