NFL PREVIEW Tonight’s game

SAN FRANCISCO at ARIZONA

Kickoff: 8:30 p.m.

TV: ESPN

Opening line: Cardinals by 11. Record vs. spread: San Francisco 2-6; Arizona 6-2.

Series history: 49ers lead 19-15. Last meeting: Cardinals 23, 49ers 13, Sept. 7, 2008.

Notebook: 49ers are one of two teams to win at Arizona since Ken Whisenhunt became Cardinals coach, 37-31 overtime victory on Nov. 25 last year. ... 49ers coach Mike Singletary, in his second game since he replaced Mike Nolan, has benched turnover-plagued QB J.T. O’Sullivan and will give journeyman Shaun Hill his third career start. ... RB Frank Gore has caught pass in each of last 40 games he’s played. ... When 49ers played at Arizona on Monday night, Sept. 27, 1999, San Francisco QB Steve Young was injured and never played again. ... Cardinals have won five straight at home ... Arizona QB Kurt Warner is on track to statistically have his best season. Halfway through season, he’s completed 70 percent of passes for 2,431 yards and 16 touchdowns with six interceptions, three of them in one game. ... Cardinals lead league in scoring at 29 points per game and have averaged 34 in three home victories. ... Arizona rookie RB Tim Hightower will get his second start in place of Edgerrin James after rushing for 109 yards, including 30-yard touchdown run against Rams.

Associated Press