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INDIANAPOLIS (4-4) At PITTSBURGH (6-2)

Game time: 4:15 p.m. TV/Radio: (27) (19) (2) (WNIO-AM 1390) Opening line: Off. Record vs. spread: Indianapolis 2-6; Pittsburgh 4-4. Series record: Steelers lead 14-5. Last meeting: Steelers 21, Colts 18, AFC divisional playoff, Jan. 15, 2006. Notebook: Steelers have dominated Colts like few other teams, winning 19 of 24, counting their 5-0 record in playoffs. Pittsburgh may have kept top-seeded Colts out of Super Bowl by winning their last meeting; Steelers went on to win Super Bowl that season, and Colts won it year later. ... Colts have lost last 12 in Pittsburgh, counting playoffs, a 40-year run that dates to their only victory there on Sept. 29, 1968, when then-Baltimore Colts won 41-7 in now-demolished Pitt Stadium. At that time, Colts QB Peyton Manning’s father, Archie, was sophomore QB at Mississippi. ... Colts are 1-10 in regular-season games in Pittsburgh. ... Colts coach Tony Dungy, a former Steelers player and defensive coordinator, is 2-3 against his former team. ... Colts TE Dallas Clark is averaging 79.3 yards in receptions last three games. ... Steelers are 5-0 against AFC. ... Steelers RB Willie Parker is averaging 101.5 yards in his last nine home games. ... WR Hines Ward has three TDs in last two games vs. Colts. ... LB LaMarr Woodley has 81‚Ñ2 sacks in his last six games and LB James Harrison has seven sacks in his last five games. They form NFL’s top sacks tandem with combined 191‚Ñ2, 10 by Harrison. ... Steelers’ 212-82-1 home record leads league since AFL-NFL merger in 1970. ... Pittsburgh is beginning first three-game homestand since September 1996, when it swept Ravens, Bills and Oilers while going 7-1 at home that season. Next up: San Diego on Nov. 16, followed by Cincinnati four days later. ... Steelers also were 6-2 at midseason a year ago. ... With league-high 32 sacks, Steelers are on pace to easily break club record of 55 in 1994 and 2001. ... This is tough matchup for Colts’ running game. Indianapolis averages league-low 70.1 yards rushing — same average Steelers’ defense allows. Pittsburgh held Washington’s Clinton Portis, NFL’s leading rusher, to 51 yards on 13 carries Monday. ... After adding new long snapper (Jared Retkofsky) last week due to injury, Steelers will debut punter Paul Ernster, who replaces ineffective Mitch Berger.

GREEN BAY (4-4) AT MINNESOTA (4-4)

Game time: 1 p.m. TV: (17/62) (8) (53) Opening line: Vikings by 3. Record vs. spread: Green Bay 5-3-0, Minnesota 3-5-0. Series record: Packers lead 49-45-1. Last meeting: Packers 24, Vikings 19, Sept. 8, 2008.

TENNESSEE (8-0) At CHICAGO (5-3)

Game time: 1 p.m. Opening line: Titans by 3. Record vs. spread: Tennessee 7-0-1; Chicago 4-3-1. Series record: Bears lead 5-4. Last meeting: Bears 19, Titans 17 in OT, Nov. 11, 2004.

NEW ORLEANS (4-4 ) At ATLANTA (5-3)

Game time: 1 p.m. Opening line: Even. Record vs. spread: New Orleans 5-3, Atlanta 5-3. Series record: Falcons lead 43-34. Last meeting: Saints 34, Falcons 14, Dec. 10, 2007.

SEATTLE (2-6) At MIAMI (4-4)

Game time: 1 p.m. Opening line: Dolphins by 9. Record vs. spread: Miami 5-3; Seattle 3-5. Series record: Dolphins lead 8-4. Last meeting: Seahawks 24, Dolphins 17, Nov. 21, 2004 at Seattle.

BALTIMORE (5-3) AT HOUSTON (3-5)

Game time: 1 p.m. TV: (27) (19) (2) Opening line: Ravens by 2. Record vs. spread: Baltimore 6-2, Houston 3-5. Last meeting: Ravens 16, Texans 15, Dec. 10, 2005.

JACKSONVILLE (3-5) At DETROIT (0-8)

Game time: 1 p.m. Opening line: Jaguars by 7. Record vs. spread: Jacksonville 2-6; Detroit 3-5. Series record: Jaguars lead 2-1. Last meeting: Jaguars 23, Lions 17 in OT, Nov. 14, 2004.

BUFFALO (5-3) At NEW ENGLAND (5-3)

Game time: 1 p.m. Opening line: Patriots by 31‚Ñ2. Record vs. spread: Buffalo 4-4; New England 4-4. Series record: Patriots lead 55-40-1. Last meeting: Patriots 56, Bills 10, Nov. 18, 2007.

CAROLINA (6-2) At OAKLAND (2-6)

Game time: 4:05 p.m. Opening line: Panthers by 71‚Ñ2. Record vs. spread: Carolina 4-3-1; Oakland 3-5. Series record: Raiders lead 2-1. Last meeting: Raiders 27, Panthers 24, Nov. 7, 2004.

KANSAS CITY (1-7) At SAN DIEGO (3-5)

Game time: 4:15 p.m. Opening line: Chargers by 14. Record vs. spread: Kansas City 4-4; San Diego 3-4-1. Series record: Chiefs lead 50-45-1 Last meeting: Chargers 24, Chiefs 10, Dec. 2, 2007.

NEW YORK GIANTS (7-1) AT PHILADELPHIA (5-3)

Game time: 8:15 p.m. TV: (21) (3) (11) Opening line: Eagles by 3. Record vs. spread: New York 5-2, Philadelphia 5-2. Series record: Giants lead 81-68-2. Last meeting: Giants 16, Eagles 13, Dec. 9, 2007.

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