NFL PREVIEW Tonight’s game

SAN FRANCISCO (2-6) At SEATTLE (4-4)

Time/TV — 8:30 p.m., ESPN

Opening line — Seahawks by 9 1/2.

Record vs. spread — 49ers 2-5-1; Seahawks 3-4-1.

Series record — Seahawks lead 9-8.

Last meeting — Seahawks 23, 49ers 3, Sept. 30, 2007 at San Francisco.

Last week — 49ers lost to Falcons 20-16; Seahawks lost to Browns 33-30 in OT.

49ers offense — OVERALL (32), RUSH (26), PASS (32)

49ers defense — OVERALL (20), RUSH (24), PASS (14)

Seahawks offense — OVERALL (13), RUSH (23), PASS (10)

Seahawks defense — OVERALL (17), RUSH (13), PASS (25)

Streaks, stats and notes — San Francisco hasn’t scored 20 points in a game since its season-opening 20-17 win over Arizona. ... Last week, 49ers played without leading rusher Frank Gore (sore ankle). Gore (435 yards, 110 carries) has yet to rush for more than 100 yards this season. ... 49ers have lost six straight. ... 49ers are last in league in total offense (224.3) and passing offense (132.8). ... In past three vs. Seattle, RB Frank Gore has 537 yards from scrimmage (179 per game), including 435 yards rushing (145 per game) and 11 catches for 102 yards with a TD. ... WR Darrell Jackson returns to Seattle after spending previous seven seasons with Seahawks (2000-06). ... Rookie LB Patrick Willis, team’s tackle leader (109), had his first career sack last week. Willis has had at least 10 tackles in each game this year. ... Seattle blew 21-6 lead last week. ... QB Matt Hasselbeck is 7-2 in his career as starter vs. 49ers, completing 192 of 301 passes (63.8 percent) for 2,448 yards with 19 TDs and nine INTs. ... Bobby Engram had career-high 14 catches for 139 yards last week. ... WR Deion Branch (22 receptions, 343 yards) had seven catches for 130 yards in last meeting with 49ers. ... LB Julian Peterson, with 17 sacks in past 24, had career-high three sacks in last meeting. ... CB Marcus Trufant, who has three INTs in past five games, had career-high two INTs in last meeting. ... RB Shaun Alexander, who has 11 TDs (10 rushing, 1 receiving) in 11 meetings with San Francisco, is likely to play despite injuring his knee last week. Alexander needs two TDs rushing to reach 100 for his career. ... Coach Mike Holmgren is 12-5 vs. 49ers.

Associated Press