Herbal remedy may not deserve popularity



LOS ANGELES TIMES
Red clover is commonly used in agriculture for its beneficial effects on soil -- and many herbalists believe it's good for people, too.
The plant's pink-and-purple flowers contain a form of vitamin E called tocopherol and compounds called isoflavones, also known as plant estrogens.
Because of similarities between isoflavones and the human hormone estrogen, red clover extract has gained popularity as a treatment for symptoms of menopause, but recent evidence casts doubt on its effectiveness.
Uses: Red clover has been used as an herbal remedy to treat conditions from eczema to asthma. In recent years, it's been marketed to prevent hot flashes, night sweats, vaginal dryness, bone deterioration and other symptoms associated with menopause. The plant is recommended by some alternative medicine practitioners to help ward off heart disease and cancer, but there's little clinical evidence to support such uses.
Dose: For symptoms of menopause, manufacturers suggest 40 milligrams of isoflavones a day in pill form or two to three cups of red clover tea.
Precautions: Because isoflavones are thought to act like estrogen, they should be avoided by women on estrogen-based contraceptives. People taking blood thinners should also avoid red clover supplements as they may amplify the effects of such drugs.
Research: Small studies conducted over the past few years showed that red clover extract might play a role in alleviating symptoms associated with menopause. But a larger study published last week in the Journal of the American Medical Association showed that it was no more effective than a placebo. Some studies have suggested that red clover isoflavones might have a beneficial effect on cholesterol levels, but more research is needed to confirm the existing evidence.
Dietary supplement makers are not required by the U.S. government to demonstrate that their products are safe or effective. Ask your health-care provider for advice on selecting a brand.