PREVIEW Seahawks at 49ers

Time: 4:15 p.m.
Series history: 49ers lead 5-2. 49ers beat Seahawks 28-21 on Oct. 14 at Seattle.
Last week: Seahawks beat Chiefs 39-32; 49ers lost to Eagles 38-17.
Key matchup: Seahawks' leaky run defense vs. 49ers RB Garrison Hearst. 49ers are 13-1 when Hearst rushes for 100 yards in a game. Averaging 4.9 yards per carry, Hearst might not get much resistance from Seahawks. Seattle allows whopping 174.4 yards per game on ground, 35.1 yards more than second-worst NFL team.
Streaks, notes and stats: Seahawks QB Matt Hasselbeck has completed 66.5 percent of passes (135 of 203), second best in NFC. ... 49ers have NFL-low nine giveaways in 2002 and rank fourth in NFL with plus-9 turnover differential. Seahawks are plus-3. ... Seahawks RB Shaun Alexander rushed for season-high 145 yards last week. He has six career 100-yard rushing games and team 6-0 in those contests. ... 49ers rookie K Jeff Chandler made NFL debut last week and connected on only FG attempt (35 yards) and both PATs.
-- Associated Press